I'd be interested in troubleshooting it with you, but right now I'm traveling. Anyway, as mentioned before I can strongly recommend an external mouse no matter what. The right tools always makes work more efficient. That said, I can understand it's annoying that it doesn't work from the touchpad, so let's try to figure it out.
Btw, you indicated you use 12.2.1, the latest version is 12.2.2, some small bug fixes (not related to this).